Creatinine Clearance (Cockcroft-Gault Equation)

The original Cockcroft-Gault equation, derived in 1976, relied on non-standardized creatinine measurements. With the use of internationally standardized creatinine measurements, the equation significantly overestimates the GFR (10-40%).
Because it includes weight in the equation, the output of the CG equation is in ml/min (compare to MDRD or CKD-EPI, with output units of ml/min/1.73m2).

From Dan Brown, PharmD, at Palm Beach Atlantic University, the primary author of the functional range of creatinine clearance paper:

“The Cockcroft-Gault equation remains the gold standard after almost 40 years, despite inaccuracies that arise from variations in body composition among patients. Those who understand potential sources of error can adjust accordingly.”

Creatinine Clearance (Cockcroft-Gault Equation)

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Creatinine Clearance (Cockcroft-Gault Equation)

Education

Medication

Video courses

ECG academy

ECG Quizzes

Education

ECHO academy

Clinical cases

ICU School

navigation

Home

Workshop

About

Privacy policy

Membership

stay in touch

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