Mechanism of action
Mainly used as a vasoconstrictor.
Sympathomimetic agent acting directly on alpha and beta adrenoreceptors and indirectly causing release of noradrenaline at sympathetic nerve endings.
Indications and dose
Side-effects
Hypertension
Bradycardia
Arrhythmias
Pharmacokinetics
Onset: seconds (IV), 10-20 minutes (IM)
Duration: 60 minutes (IV/IM)
Bioavailability: >90%
Metabolism: Hepatic
Half-life of elimination: 3-6 hours
Excretion: Urine
Directions for administration
Dilute in e.g. 10 ml of 0.9% sodium chloride.
Medicinal forms
1 vial = 30 mg in 1 ml
1 vial = 50 mg in 1 ml
References
