Mechanism of action
Anticoagulant.
Synthetic pentasaccharide inhibits activated factor X via antithrombin III.
Indications and dose
Side-effects
Anaemia
Bleeding
Pharmacokinetics
Routes: Subcutaneous, Intravenous
Onset: Rapid
Bioavailability: 100%
Metabolism: None
Half-life of elimination: 17-21 hours
Excretion: Urine
Directions for administration
Fore subcutaneous injection use alternate sites.
Do not administer intramuscularly.
For intravenous use (off-label) use as bolus dose or mix with 0.9% sodium chloride.
Medicinal forms
Solution for injection
1 vial = 5 ml (2.5 mg), 4 ml (5 mg), 6 ml (7.5 mg), 8 ml (10 mg)
References
