Mechanism of action
Used mainly as a peripheral vasopressor.
Sympathomimetic agent acting on alpha (predominantly) and beta adrenoreceptors, increasing heart rate, myocardial contraction and blood pressure.
Indications and dose
Side-effects
Arrhythmias
Headache
Hypertension
Skin tissue necrosis
Reflex bradycardia
Pharmacokinetics
Onset: 1-2 minutes
Duration: 20-60 minutes
Metabolism: Liver
Half-life of elimination: minutes
Directions for administration
Dilute in 0.9% sodium chloride or 5% glucose. Suggested volume ranges from 20-500 ml.
Can be administered via peripheral venous catheter.
Medicinal forms
1 vial = 2.5 mg in 5 ml (0.5 mg in 1 ml)
References
