Mechanism of action
Used as peripheral vasopressor.
Sympathomimetic agent with predominantly alpha1-adrenergic receptor activity causing peripheral vasoconstriction and reflex bradycardia.
Indications and dose
Side-effects
Reflex bradycardia
Arrhythmias
Headache
Hypertension
Myocardial ischaemia
Reflex bradycardia
Contraindications
Pheochromocytoma
Pharmacokinetics
Onset: 1 minute
Duration: 20 minutes
Metabolism: Hepatic
Half-life of elimination: 2-3.5 hours
Directions for administration
Dilute with 5% glucose or 0.9% sodium chloride.
Can be administered via peripheral venous catheter.
Medicinal forms
1 vial = 10 mg in 1 ml
References
